IUI Treatment enjoys the status of being one of the most popular treatment modality in infertility in recent years in India. The very fact that IUI treatment is simple, inexpensive, easy and affordable and makes many clinicians to opt for this method.
The history of IUI process dates back to 1770 when John Hunter advised a man to inseminate his wife with his semen collected in a warm syringe. This indication was that of hypospadias. This resulted in pregnancy. In the 19th century, Marion Sims carried out inseminations in 6 women. He got success in only one woman. In 1953, Bunge and Sherman reported the first pregnancy from the stored frozen semen.
The IUI Treatment India is highly demanded globally due to its cost effectiveness and quality. IUI treatment India is a part of global medical tourism.
IUI treatment was not practiced till recently due to the fact that direct insemination into the uterus without a wash (preparation of sperms) causes severe uterine cramps due to the presence of prostaglandins. The advent of in vitro fertilization and embryo transfer (IVF-ET) and other assisted reproductive techniques (ART) which utilize the sperm wash techniques with ovarian stimulation have led to the practice of IUI.
When considering fertility treatments above and beyond fertility drug use, IUI procedure may be the first line of treatment. It’s easier to do and costs much less. It is a painless, precise, simple, easy and atraumatic technique. A bolus of concentrated, motile, morphologically normal and capacitated sperms are deposited in the uterine cavity very near to the opening of the Ostia of fallopian tubes at the time of ovulation.
IUI treatment cost in India is reasonable. Safal IVF Fertility Foundation in Ahmedabad offers the best and affordable IUI fertility treatment. The IUI success rates are very high.
IUI relies on the natural ability of sperm to fertilize an egg within the reproductive tract and hence there are specific indications where IUI will be effective.
In 1980s, direct intraperitoneal insemination (DIPI) was occasionally used, where clinicians injected sperm into the lower abdomen through a surgical hole or incision, with the intention of letting the sperms find the oocyte at the ovary or after entering the genital tract through the ostium of the fallopian tube.
The selection of patients for IUI has to be very appropriate. In the male, there should be at least 10 million motile sperms and in females, the age should be less than 40 years and at least one fallopian tube must be patent. Endometrium should be normal and the ovaries should be capable of ovulating. It is also mandatory that the sperms should be able to fertilize the oocyte.
In unexplained infertility, the sperm may be inserted within a larger volume of fluid than usual so as to reach up into the fallopian tubes more easily. This technique takes a few minutes more than standard IUI and is known as “fallopian sperm perfusion”. It has been shown to increase the chances of success in cases of unexplained infertility.
The advent of Medically Assisted Reproductive Techniques (MART) has not only gifted the world with new creation of life but also with newer fertility techniques for reproduction. IVF-ET has given birth to IUI. The necessity of having sperm wash techniques for IVF resulted in clinician’s using this modality as a treatment. Though the advent of artificial insemination is very old and dates back to the 18th century, the first ever-published article on IUI is only during the 20th century.
Initially, IUI was thought to benefit patients with only cervical infertility or hostility. In the present scenario, cases of unexplained infertility, immunological infertility and endometriosis also benefits from this treatment option.
Medically assisted reproductive technologies include the involvement of both the gametes. Intrauterine insemination (IUI) is a technique where only the male gamete is manipulated. Technically speaking IUI comes under alternate assisted reproductive technique.
There is also, donor insemination available using, frozen, quarantined and tested samples for therapeutic donor insemination (TDI). The use of cryopreserved semen in donor insemination programme is now mandatory in most countries to minimize the possibility of transmission of human immunodeficiency virus (HIV) to the recipients.
The ability of the sperm to fertilize cannot be known by IUI. The only method by which the fertilizing capacity of sperms can be known is IVF-ET. This is how IVF-ET has an edge over IUI. IUI is only treatment modality whereas IVF-ET has both therapeutic and diagnostic value.
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